The Associate Biomedical Modeler performs basic pharmacometric modeling and/or statistical analysis to support laboratory and/or clinical research projects. Performs these tasks independently and generally using widely accepted approaches.

The Center for Translational Pharmacology (CTP) at St. Jude Children's Research Hospital has an open position for a highly motivated and creative individual at the Associate Biomedical Modeler level within the Department of Pharmacy and Pharmaceutical Sciences. The CTP is the nexus for clinical pharmacology at St. Jude, where the clinical enterprise has expanded beyond oncology to programs that include non-malignant hematology, cell therapy, infectious diseases, neurologic diseases, epidemiology, and psychology.

Scientists with expertise in innovative pharmacometric and statistical approaches for pharmacokinetic and pharmacodynamic data analysis are encouraged to apply. The biomedical modeling group is integral to clinical trial design and interpretation, and scientists are expected to contribute to manuscript preparation with appropriate credit on publications. Additional opportunities for scholarship through novel modeling approaches are encouraged and CTP scientists will have the opportunity for continued professional development through training and participation in scientific conferences. The CTP provides a highly interactive environment with collaborative opportunities for meaningful contributions to the design of all pharmacology aspects within the context of phase 0, phase I, and phase II clinical trials. CTP biomedical modelers will interact with faculty in the Department of Pharmacy and Pharmaceutical Sciences and clinicians across all clinical research programs.

Associate Biomedical Modeler

Job Responsibilities:

• Provide pharmacometric expertise to researchers as designated by collaboration areas in all aspects of conducting pharmacometric and/or statistical analyses for basic, translational, and/or clinical studies. Assists with acquiring or acquires the data for modeling and verifies the data prior to modeling.
• Understand, integrate, and use widely accepted approaches to pharmacometric modeling and statistical analysis (e.g., R, Matlab).
• Utilize routine pharmacometric software (e.g., ADAPT, NONMEM, Monolix, WinNonlin, SimCYP, PK Sim, MOBI, GastroPlus) to conduct noncompartmental as well as compartmental analyses.
• Perform and document mathematical modeling and statistical analysis of research data and prepare the results in an accepted format.
• Assist in maintaining and developing SOPs, policies, and procedures pertaining to or interfacing with pharmacometric activities.
• Participate in the development of software interfaces for clinical programs necessary for pharmacokinetic and drug dosage adjustment for clinical protocols.
• Performs other related duties as assigned to meet the goals and objectives of the department and institution
• Maintains regular and predictable attendance.

Minimum Education and/or Training:

• Bachelor’s degree in biostatistics, statistics, or related field.
• Master’s degree in biomedical science, mathematics, computer science or other related field preferred. PhD is highly preferred.

Minimum Experience:

• Two (2) years’ experience in an academic or industrial staff position or substantial participation in mathematical modeling required.
• Advanced training in systems modeling and/or data handling and analysis required.
• Experience with pharmacometric and/or biomedical modeling projects is preferred.

Compensation

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $78,000 - $139,360 per year for the role of Associate Biomedical Modeler.

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